Mustafa Emre Bakırcıoğlu

Mustafa Emre Bakırcıoğlu
DegreeAssoc. Prof. Dr.
Areas of expertiseErectile dysfunction Neurourology Male Infertility
LanguagesEnglish / Turkish
Working DaysMonday - Saturday

Emre Bakircioglu, MD is an expert of male reproductive health and skilled surgeon especially in azoospermic patients with testicular sperm production failure. He has been performed enormous number (more than 5000 micro-TESE operations including in Turkey and other various countries) with a high success rate. He is known as a modest and compassionate physician who really cares and gentle to his patients. He is pleased to be supporting the couples from all over the world, during the most challenging process of their lives and provide them contemporary treatment modalities. He is currently working as a visiting Urologist in several hospitals in Istanbul.


Postdoctoral Fellow: Neurourology/Erectile Dysfunction: University California, San Francisco Department of Urology under supervision of Prof. Dr. Tom Lue, 1996-1999.

Resident: Haydarpaşa Numune Hospital, Department of Urology, 1992-1997..

MD : Istanbul University, Cerrahpaşa Medical School, 1984-1990.

High School : Ozel Moda High School, 1984

Professional Experience
  1. Private Clinic December 2014.
  2. Umut Bahceci IVF Center, Istanbul Urology/Andrology, 2006-2014.
  3. German Hospital, Istanbul Urology/Andrology Department of Urology, 2004-2009.
  4. Istanbul Memorial Hospital Urology/Andrology IVF Center, 2002-2004.
  5. Altıntepe Kızılay Medical Center, Istanbul Urology, 2000-2002.
  1. Lapides Essay Contest: Second Place Winner, American Urological Association 2000, Atlanta. USA
  2. Yamanuchi Prize winner ‘The best abstract in impotence category’ American Urological Association 2000, Atlanta, USA
  3. Basic Science Section, International Bladder Symposium: Second prize 1999, USA.
  4. Bard-Preis Award. Weisbaden, 1999, Germany.
  5. Joseph F. McCarthy/Circon ACMI Physician Essay Contest: First Place, Western Section American Urological Association 1998, USA.
  6. Lapides Assay Contest: Certificate of Honorable Mention, 1997, USA.
  1. Turkish Society of Urological Surgery
  2. Turkish Urology Association
  3. Turkish Society of Andrology
  4. Turkish Society for Reproductive Medicine (TSRM)
  5. Ureme Tibbi ve Cerrahisi Dernegi (UTD)
  6. European Association of Urology (EAU)
  7. American Urological Association (AUA)
  8. American Society for Reproductive Medicine (ASRM)
  9. Society for Male Reproduction and Urology (SMRU)
  1. Dahiya, R., Lin, A., Bakircioglu, M.E., Huang, S-T and Lue, T.F.: mRNA and protein expression of nitric oxide synthase and adrenoceptor alpha-1 in young and old rat penile tissues. Br J Urol. 1997 Aug;80(2):300-6.
  2. Lin, C.-S., Lau, A., Bakircioglu, E., Tu, R., Wu, F., Week, S., Nunes, L. and Lue, T.F.: Analysis of neuronal nitric oxide synthase isoform expression and identification of human nNOS-m. Biochem Biophys Res Commun. 1998 Dec 18; 253(2):388-94.
  3. El-Sakka, A., Hassan, M.U., Bakircioglu, M.E., Pillarisertty, R.J., Dahiya, R., and Lue, T.F.: Possible molecular mechanisms of cryoablation-induced impotence in a rat model. Urology. 1998 Dec;52(6):1144-50.
  4. el-Sakka, A. I., Bakircioglu, M. E., Bhatnagar, R. S., Yen, T. S., Dahiya, R., and Lue, T. F. The effects of colchicine on a Peyronie's-like condition in an animal model. J. Urol. 1999 Jun;161(6):1980-3.
  5. Bakircioglu, M.E., Sievert, K.-D., Lau, A., Lin, C.-S., and Lue, T.F.: The Effect of Pregnancy and Delivery on the Function and Ultrastructure of the Rat Bladder and Urethra. Br. J. Urol. 2000 Feb;85(3):350-61.
  6. Sievert, K.-D., Bakircioglu, M.E., Nunes, L., Tu, R., Dahiya, R., and Tanagho, E.A.Homologous Acellular Matrix Graft for Urethral Reconstruction in the Rabbit: Histologic and Functional Evaluation. J. Urol.2000 Jun;163(6):1958-65.
  7. Bakircioglu, M.E., Hsu, K., El-Sakka, A., Sievert, K.-D., Lin, C.S., and Lue, T.L.: The effect of a Chinese herbal medicine mixture on a rat model of hypercholesterolemic erectile dysfunction. J Urol. 2000 Nov;164(5):1798-801.
  8. Bakircioglu, M.E., Lin, C.S., Fan, P., Sievert, K.-D, Kan, Y.W., and Lue, T.F.: The effect of adeno-associated virus-mediated brain-derived neurotrophic factor in an animal model for neurogenic impotence. J. Urol. 2001 Jun (6 Pt 1);165:2103-2109.
  9. Sievert, K.D., Wefer, J., Bakircioglu, M.E., Nunes, L., Dahiya, R., and Tanagho, E.A.: Heterologous acellular matrix graft for recontriction of the rabbit urethra: histological and functional evaluation. J. Urol. 2001 Jun;165(6 Pt 1):2096-2102.
  10. Sievert, K.-D., Emre Bakircioglu, M., Tsai, T., Dahms, S. E., Nunes, L., and Lue, T. F. The effect of simulated birth trauma and/or ovariectomy on rodent continence mechanism. Part I: Functional and Structural Change. J Urol. 2001 Jul;166(1):311-7.
  11. Bakircioglu, M.E., Sievert, K.-D., Nunes, L., Lau, A., Lin, C.-S., and Lue, T.F.: Decreased trabecular smooth muscle and caveolin-1 expression in the penile tissue of aged rats. J. Urol 2001 Aug.; 166(2):734-8.
  12. Wefer, J., Sekido, N., Sievert, K.-D., Wefer, A. E., Nunes, L., Bakircioglu, M. E., Dahiya, R., and Tanagho, E. A.: Tunica albuginea acellular matrix graft for penile reconstruction in the rabbit: a model for treating Peyronie's disease. BJU Int. 2002 Aug;90(3):326-31.
  13. Kahraman S., Findikli N., Berkil H., Bakircioglu E., Sertyel S. and Biricik A.: Results of preimplantation genetic diagnosis in patients with Klinefelter’s syndrome. RBM online 2003 Oct.; 7 (3): 346-352.
  14. Sievert K.-D., Bakircioglu M.E., Tsai T., Nunes L., Lue T.F.: The effect of labor and/or ovariectomy on rodent continence mechanism--the neuronal changes.World J Urol. 2004 Oct.; 22(4):244-50.
  15. Bakircioglu M.E., Erden H.F., Kaplancan T., Cıray N., Bener, F., Bahceci M.: Aging may adversely affect testicular sperm recovery in patients with Klinefelter’s syndrome. Urology 2006 Nov.; 68 (5):1082-1086.
  16. Bakircioglu M.E., Erden H.F., Ciray H.N., Bayazit N., Bahceci M.: Gonadotrophin therapy in combination with ICSI in men with hypogonadotrophic hypogonadism. Reproductive BioMedicine Online 2007 Aug.; 15 (2): 156-160.
  17. Bakircioglu M.E., Ulug U, Erden H.F., TosunS., Bayram A., Ciray N., Bahceci M.: Klinefelter’s syndrome: does it confer a bad prognosis in the treatment of nonobstructive azoospermia? Fertil Steril. 2011 Apr;95(5):1696-9.
  18. Bakircioglu M.E., Tulay P., Findikli N., Erzik B., Gültomruk M., Bahceci M.: Successful sperm recovery and IVF treatment in a man with Leydig cell hypoplasia J Asist Reprod Genet. 2014 Jul;31(7):817-21.
  19. Ramasamy R., Bakircioglu M.E., Cengiz C., Karaca E., Scovell J., Jhangiani S. N., Akdemir Z.C., Bainbridge M., Yu Y., Huff C., Gibbs R. A., Lupski J. R., Lamb D. J. Fertil Steril 2015 Aug;104(2):286-91. Whole-exome sequencing identifies novel homozygous mutation in NPAS2 in family with nonobstructive azoospermia.
  20. Okutman O., Muller J., Baert Y., Serdarogulları M., Gultomruk M., Piton A., Rombaut C., Benkhalifa M., Teletin M., Skory V., Bakircioglu E., Goossens E., Bahceci M., Viville S. Exome sequencing reveals a nonsense mutation in TEX15 causing spermatogenic failure in a Turkish family. Hum Mol Genet. Oct 1;24(19):5581-8.
  21. Okutman O, Muller J, Skory V, Garnier JM, Gaucherot A, Baert Y, Lamour V, Serdarogullari M, Gultomruk M, Röpke A, Kliesch S, Herbepin V, Aknin I, Benkhalifa M, Teletin M, Bakircioglu E, Goossens E, Charlet-Berguerand N, Bahceci M, Tüttelmann F, Viville S. A no-stop mutation in MAGEB4 is a possible cause of rare X-linked azoospermia and oligozoospermia in a consanguineous Turkish family. J Assist Reprod Genet. 2017 May;34(5):683-694.
  22. Clavijo RI, Bakircioglu E, Ramasamy R. Re: Predictive Factors for Sperm Recovery after Varicocelectomy in Men with Nonobstructive Azoospermia: K. Shiraishi, S. Oka and H. Matsuyama. J Urol. 2017 May 2. pii: S0022-5347(17)40344-2
  23. Clavijo RI, Arora H, Gibbs E, Cohen S, Griswold A, Bakircioglu E, Bademci G, Tekin M, Ramasamy R. Whole Exome Sequencing of a Consanguineous Turkish Family Identifies a Mutation in GTF2H3 in Brothers with Spermatogenic Failure. Urology. 2018 Jun 30. pii: S0090-4295(18)30622-8. doi: 10.1016/j.urology.2018.06.031. [Epub ahead of print] PMID: 29966603
  24. Buran A, Tulay P, Dayıoğlu N, Bakircioglu ME, Bahceci M, İrez T. Evaluation of the morphokinetic parameters and development of pre-implantation embryos obtained by testicular, epididymal and ejaculate spermatozoa using time-lapse imaging system. Andrologia. 2018 Dec 19:e13217. doi: 10.1111/and.13217.
  25. Agarwal A., Parekh N., Selvam M.K.P., et al.: Male oxidative stress infertility (MOSI): Proposed terminology and clinical practice guidelines for management of idiopathic male infertility. World J Mens Health. 2019;37:e24.
  26. Ozman O., Bakircioglu ME.: The clinical impact of parenteral consanguineous marriage in idiopathic non-obstructive azoospermia. F&S Reports Open Access DOI:
  27. Özman O, Tosun S, Bayazıt N, Cengiz S, Bakırcıoğlu ME: Efficacy of the Second Micro-TESE after First Micro-TESE in Men with Nonobstructive Azoospermia. F&S Accepted October 2020.
Invited Speaker
  1. 4th National Congress of Sterility, Contraception and Hormone Replacement Therapy Management of Non-Obstructive Azoospermia, 9-12 March, 2003, Borovetz, Bulgaria.
  2. The Second International Congress of the Jordanian Society for Fertility and Genetics: Infertility Treatment of Men with Klinefelter’s Syndrome, 4-7 April, 2007, Amman, Jordan.
  3. 6th Annual Meeting Mediterranean Society for Reproductive Medicine: Methods for Sperm Retrieval in Azoospermia, 20-23 April, 2007, Antalya, Turkey.
  4. 7th Annual Turkish Andrology Society Meeting: Medical Treatment in Men with Hypogonadotrophic Hypogonadism, 6-9 June, 2007, Ankara, Turkey.
  5. Basel University Department of IVF Center and Urology: Outcome of Microdissection TESE in Different Etiological Pattern of 970 Nonobstructive Azoospermic Patients, 15 January 2009, Basel, Switzerland.
  6. II. Ureme Tibbi Dernegi Kongresi: Klinefelter’s syndrome and assisted reproductive technologies, 1-4 October, 2009, Antalya, Turkey.
  7. University of Tubingen, Department of Urology: The Combination of Gonadotrophin Therapy and Intracytoplasmic Sperm Injection in the Treatment of Hypogonadotrophic Hypogonadism., 19 January 2009, Tubingen, Germany.
  8. III. Ureme Tibbi Dernegi Kongresi: Comparison of ICSI Outcomes of Men with Klinefelter Syndrome and Men with Nonobstructive Azoospermia, 5-9 October, 2011, Antalya, Turkey.
  9. Society for Urologic Surgery in Turkey: Online Asistan eğitim programı İnfertilite, Androloji, Enfeksiyon. Sperm elde etme teknikleri, yardımcı üreme teknikleri 22 February 2014, Izmir, Turkey.
  10. ASPIRE IV Meeting. What every Gynecologist must know about male infertility: Update, Bodrum Turkey, 3-4 May,2014.
  11. 1st Greek-Turkish Urological Meeting. Overcoming frontiers in modern Urology. Contemporary management of infertile couple. Thessaloniki, Greece, 12-14 September 2014.
  12. 2nd National Urological Surgery Meeting: Micro TESE surgery and what to do after unsuccessful Micro TESE operation? November 8 2014, Antalya Turkey.
  13. TESE nasıl yapılmalı, başarısız olgulara ne yapılmalı? Pratik Kurs V 2. Ulusal Ürolojik Cerrahi Kongresi Antalya, 5-9 Kasım 2014.
  14. Peyronie Hastalığının Medikal Tedavisi. Ürolojik Cerrahi Derneği, Çanakkale Toplantısı, 23 Mayıs 2015.
  15. Erkek infertilitesi ve Olgular eşliğinde infertile hastaya yaklaşım ve medikal tedavi. ‘Genç Ürolologlar Yetişiyor’ Ürolojik Cerrahi Derneği Eğitim Programı, Tuzla Radisson Blue Hotel, 28-31 Mayıs, 2015.
  16. Azoospermik Erkeğin değerlendirilmesinde optimal yaklaşımlar. Androloji Rekonstrüktif Grubu Toplantısı, 3. Ulusal Ürolojik Cerrahi Derneği, Antalya 2-6 Kasım 2016.
  17. Erkek İnfertilitesinde Genetik Yaklaşımlar Oturum III, Ulusal Ürolojik Cerrahi Derneği, Antalya 2-6 Kasım 2016.
  18. Nonobstrüktif azoospermic erkeklerde TESE öncesi tedavi ve varikosel operasyonu yapılmalı mı? Çapraz Ateş IV, Ulusal Ürolojik Cerrahi Derneği, Antalya 2-6 Kasım 2016.
  19. İnfertil Erkeğin Medikal Tedavisi. Androloji Rekonstrüksiyon Kurs XIII, Ulusal Ürolojik Cerrahi Derneği, Antalya 2-6 Kasım 2016.
  20. Erkek İnfertilitesinde Zor Vakalar. Androloji Rekonstrüksiyon Kurs XIII, Ulusal Ürolojik Cerrahi Derneği, Antalya 2-6 Kasım 2016.
  21. Azospermik hastaya yaklaşım, Ürolojik Cerrahi Derneği muğla Androloji Toplantısı 31 Mart 2018, Muğla Sıtkı Koçman Üniversitesi.
  22. Onkofertilite, Ürolojik Cerrahi Derneği Muğla Androloji Toplantısı, 31 Mart 2018, Muğla Sıtkı Koçman Üniversitesi.
  23. Varikoselde güncelleme, Ürolojik Cerrahi Derneği 14-15 Nisan 2018, Sheraton Oteli, Adana.
  24. Erkek İnfertilitesi, Ürolojik Cerrahi Derneği, Araştırma Görevlisi Eğitim Programı (AGEP).
  25. IVF çağında erkek infertilitesinde varikoselin güncellenen önemi 4. Ürolojik Cerrahi Kongresi 31 Ekim-4 Kasım 2018, Antalya, Türkiye.
  26. Non-obstrüktif azospermi’de cerrahi yöntemler, Pratik Kurs-IV Androloji4. Ürolojik Cerrahi Kongresi 31 Ekim-4 Kasım 2018, Antalya, Türkiye.
  27. Onkofertilite, Kurs IX 4. Ürolojik Cerrahi Kongresi 31 Ekim-4 Kasım 2018, Antalya, Türkiye.